Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115237 | 0.94 | HSD17B10 (0.31) | ITGB3ITGA2BHTT | |
| SCHEMBL8122590 | 0.84 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL8117396 | 0.83 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL9029392 | 0.82 | OPRM1 (0.35) | ITGB3ITGA2BHTTPTPN1DGAT1 | |
| SCHEMBL7419658 | 0.82 | ITGB3 (0.36) | ITGB3ITGA2BHTTPTPN1KDM4E | |
| SCHEMBL8117806 | 0.82 | HTT (0.31) | ITGB3ITGA2BHTTPTPN1ADAM17 | |
| SCHEMBL7418903 | 0.80 | ITGB3 (0.51) | ITGB3ITGA2BHTTKDM4EALDH1A1 | |
| SCHEMBL8881209 | 0.80 | HTT (0.41) | HTTPTPN1DGAT1KDM4EALDH1A1 | |
| SCHEMBL8122599 | 0.80 | — | — | |
| SCHEMBL8109897 | 0.80 | PTPN1 (0.36) | HTTPTPN1ADAM17ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | claimed |