Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628506 | 0.79 | HIF1A (0.36) | HIF1AEPAS1ALDH1A1HPGDCYP3A4 | |
| SCHEMBL14930303 | 0.73 | HIF1A (0.42) | HIF1AEPAS1 | |
| SCHEMBL7300235 | 0.68 | CA12 (0.43) | HIF1AEPAS1ALDH1A1HPGDCYP3A4 | |
| SCHEMBL2564066 | 0.66 | ALDH1A1 (0.38) | HIF1AEPAS1ALDH1A1KDM4EPOLB | |
| SCHEMBL2008330 | 0.61 | ALDH1A1 (0.43) | HIF1AEPAS1ALDH1A1HPGDCYP3A4 | |
| SCHEMBL2004771 | 0.60 | ALDH1A1 (0.40) | HIF1AEPAS1ALDH1A1HPGDCYP3A4 | |
| SCHEMBL2012701 | 0.58 | ALDH1A1 (0.49) | HIF1AEPAS1ALDH1A1HPGDCYP3A4 | |
| SCHEMBL15989633 | 0.57 | ALDH1A1 (0.56) | HIF1AEPAS1ALDH1A1HPGDCYP3A4 | |
| SCHEMBL8810009 | 0.57 | HIF1A (0.41) | HIF1AEPAS1ALDH1A1HPGDCYP3A4 | |
| SCHEMBL10772005 | 0.56 | HIF1A (0.37) | HIF1AEPAS1ALDH1A1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147547-A1 | SUBSTITUTED HYDROXYETHYL AMINE COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE | AMGEN INC. (US) | 2008-12-04 | — | — | WO | disclosed |