Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971344 | 0.88 | ALDH1A1 (0.54) | PTGS2GAAPLAUELANENPC1 | |
| SCHEMBL4927732 | 0.72 | GAA (0.75) | PTGS2GAAPLAUELANENPC1 | |
| SCHEMBL3938137 | 0.71 | GAA (0.55) | PTGS2GAAPLAUELANENPC1 | |
| SCHEMBL3938131 | 0.71 | GAA (0.55) | PTGS2GAAPLAUELANENPC1 | |
| SCHEMBL14038095 | 0.70 | PLAU (0.54) | PTGS2GAAPLAUELANENPC1 | |
| SCHEMBL10972445 | 0.70 | GAA (0.48) | PTGS2GAAPLAUELANENPC1 | |
| SCHEMBL9110617 | 0.70 | HDAC3 (0.59) | PTGS2GAAPLAUELANENPC1 | |
| SCHEMBL2526264 | 0.69 | NPC1 (0.83) | GAANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL10972447 | 0.68 | GAA (0.49) | PTGS2GAAPLAUELANENPC1 | |
| SCHEMBL3939301 | 0.67 | CES2 (0.53) | GAANPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1010691-A2 | Hydrazide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |