Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.54 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121143 | 0.89 | AGTR1 (0.49) | AGTR1AGTR2GP6 | |
| SCHEMBL8976741 | 0.86 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL8976748 | 0.86 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL8119597 | 0.86 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL9422649 | 0.85 | AGTR1 (0.57) | AGTR1AGTR2GP6 | |
| SCHEMBL8131016 | 0.84 | AGTR2 (0.44) | AGTR1AGTR2GP6 | |
| SCHEMBL9422538 | 0.82 | AGTR1 (0.50) | AGTR1AGTR2GP6 | |
| SCHEMBL7839994 | 0.79 | AGTR1 (0.56) | AGTR1AGTR2GP6 | |
| SCHEMBL8976642 | 0.79 | GP6 (0.51) | AGTR1AGTR2GP6 | |
| SCHEMBL8976651 | 0.79 | GP6 (0.51) | AGTR1AGTR2GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581003-B1 | Imidazolyl substituted cyclohexane derivatives | BAYER AG (DE) | 2000-09-06 | — | — | EP | disclosed |
| EP-0581003-A1 | Imidazolyl substituted cyclohexane derivatives | BAYER AG (DE) | 1994-02-02 | — | — | EP | disclosed |