SCHEMBL811981

SCHEMBL811981

COc1ccc(/C=C/c2nc(N)nc(C(Cl)(Cl)Cl)n2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
DHFR P00374 1/20 0.47
CYP1A2 P05177 2/20 0.45
CYP3A4 P08684 2/20 0.45
KDM4E B2RXH2 1/20 0.45
NPC1 O15118 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
HPGD P15428 1/20 0.45
CYP2C19 P33261 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
RELA Q04206 2/20 0.44
TRPA1 O75762 1/20 0.44
NFE2L2 Q16236 2/20 0.43
AHR P35869 2/20 0.43
TUBB4A P04350 4/20 0.43
TUBB P07437 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL153282 1.00 MAPT (0.55) MAPTMEN1KMT2ADHFRCYP1A2
SCHEMBL51497 0.91 CYP1A2 (0.50) MAPTMEN1KMT2ACYP1A2CYP3A4
SCHEMBL51498 0.91 CYP1A2 (0.50) MAPTMEN1KMT2ACYP1A2CYP3A4
SCHEMBL21940412 0.91 CYP1A2 (0.50) MAPTMEN1KMT2ACYP1A2CYP3A4
Hydrogen Sulfide SCHEMBL30503988 0.90 CYP1A2 (0.49) MAPTMEN1KMT2ACYP1A2CYP3A4
SCHEMBL8852597 0.87 MAPT (0.56) MAPTMEN1KMT2ADHFRCYP1A2
SCHEMBL12595129 0.86 RELA (0.47) MAPTMEN1KMT2ACYP1A2CYP3A4
SCHEMBL12379805 0.86 RELA (0.47) MAPTMEN1KMT2ACYP1A2CYP3A4
SCHEMBL6336133 0.84 CYP1A2 (0.44) MAPTMEN1KMT2ACYP1A2CYP3A4
SCHEMBL6336130 0.84 CYP1A2 (0.44) MAPTMEN1KMT2ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5049481-A Merocyanine compound FUJI PHOTO FILM CO., LTD. (JP) 1991-09-17 US claimed
US-4239850-A PHOTOINITIATOR OF AN UNSATURATED KETONE AND A TRIHALOMETHYL TRIAZINE FUJI PHOTO FILM CO., LTD. (JP) 1980-12-16 US claimed
EP-3182204-B1 PLANOGRAPHIC PRINTING PLATE PRECURSOR USING A POLYMERIZABLE COMPOSITION FUJIFILM CORP (JP) 2021-10-20 EP disclosed
EP-3182204-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR USING A POLYMERIZABLE COMPOSITION FUJIFILM Corporation (JP) 2017-06-21 EP disclosed
EP-2109000-B1 Polymer having polymerizable group, polymerizable composition, planographic printing plate precursor, and planographic printing method using the same FUJIFILM CORP (JP) 2017-02-22 EP disclosed
EP-2105795-B1 Resin composition for laser engraving, image forming material, relief printing plate precursor for laser engraving, relief printing plate, and method of manufacturing relief printing plate FUJIFILM CORP (JP) 2016-12-28 EP disclosed
EP-1564591-B1 Polymerizable composition FUJIFILM CORP (JP) 2016-08-03 EP disclosed
EP-1471387-B1 Photosensitive composition and compound used thereof FUJIFILM CORP (JP) 2015-11-11 EP disclosed
EP-1403710-B1 Polymerizable composition FUJIFILM CORP (JP) 2015-06-10 EP disclosed
EP-2085220-B1 Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate and method of producing the same FUJIFILM CORP (JP) 2015-05-20 EP disclosed
US-8822126-B2 Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate, and method of manufacturing relief printing plate FUJIFILM CORPORATION (JP) 2014-09-02 US disclosed
EP-0497342-A2 Negative photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-08-05 EP disclosed
US-5091280-A Photothermography; microencapsulated leuco dyes, polymerizable vinyl monomer, photoinitiator electron acceptive developer FUJI PHOTO FILM CO., LTD. (JP) 1992-02-25 US disclosed
US-5049481-A Merocyanine compound FUJI PHOTO FILM CO., LTD. (JP) 1991-09-17 US disclosed
EP-0377321-A2 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1990-07-11 EP disclosed
US-4810618-A HIGH SENSITIVITY, PRINTING PLATES, PHOTORESISTS FUJI PHOTO FILM CO., LTD. (JP) 1989-03-07 US disclosed
US-4774163-A LITHOGRAPHIC PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1988-09-27 US disclosed
US-4505793-A INITIATOR IS BLEND OF 3-KETO-SUBSTITUTED CUMARIN AND HALOGEN COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1985-03-19 US disclosed
US-4258123-A UNSATURATED COMPOUND, HALOGENATED TRIAZINE, UNSATURATED KETONE FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US disclosed
US-4239850-A PHOTOINITIATOR OF AN UNSATURATED KETONE AND A TRIHALOMETHYL TRIAZINE FUJI PHOTO FILM CO., LTD. (JP) 1980-12-16 US disclosed