Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8111372 | 0.92 | MMP13 (0.37) | MMP13MAOBMMP1MMP2MMP9 | |
| SCHEMBL8127025 | 0.86 | LMNA (0.39) | MMP13MAOBMMP1MMP2MMP9 | |
| SCHEMBL8120819 | 0.86 | POLB (0.36) | MMP13MAOBNR4A2PTGS1PTGS2 | |
| SCHEMBL8112036 | 0.85 | MAOB (0.41) | MMP13MAOBHDAC1HDAC6HDAC5 | |
| SCHEMBL8126314 | 0.85 | HDAC6 (0.37) | MAOBHDAC1HDAC6HDAC5KDM4E | |
| SCHEMBL8110803 | 0.85 | NUDT1 (0.36) | MMP13MMP1MMP2MMP9KDM4E | |
| SCHEMBL8119160 | 0.84 | GRM5 (0.38) | MMP13MAOBNR4A2MAOAKDM4E | |
| SCHEMBL8127225 | 0.79 | NUDT1 (0.38) | MMP13KDM4ELMNAL3MBTL1 | |
| SCHEMBL5548596 | 0.79 | CHRM5 (0.38) | MAPK1 | |
| SCHEMBL8124547 | 0.78 | MAOB (0.40) | MAOBKDM4ELMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028959-A1 | HERBICIDAL FURANYL- AND THIENYLOXYAZINES | AMERICAN CYANAMID COMPANY (US) | 2000-08-23 | — | — | EP | claimed |
| WO-1999024427-A1 | HERBICIDAL FURANYL- AND THIENYLOXYAZINES | AMERICAN CYANAMID COMPANY (US) | 1999-05-20 | — | — | WO | claimed |
| US-5851952-A | Herbicidal thienyloxyazines | AMERICAN CYANAMID COMPANY (US) | 1998-12-22 | — | — | US | claimed |
| EP-1028959-A1 | HERBICIDAL FURANYL- AND THIENYLOXYAZINES | AMERICAN CYANAMID COMPANY (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999024427-A1 | HERBICIDAL FURANYL- AND THIENYLOXYAZINES | AMERICAN CYANAMID COMPANY (US) | 1999-05-20 | — | — | WO | disclosed |
| US-5851952-A | Herbicidal thienyloxyazines | AMERICAN CYANAMID COMPANY (US) | 1998-12-22 | — | — | US | disclosed |