Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | GRK2 | P25098 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114673 | 0.85 | ALDH1A1 (0.64) | ALDH1A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL4118287 | 0.84 | MEN1 (0.68) | ALDH1A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8112830 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTKMT2ANLRP1RAB9A | |
| SCHEMBL8104707 | 0.79 | MCHR1 (0.47) | ALDH1A1MAPTKMT2ANLRP1GAA | |
| Hydrochloric Acid SCHEMBL8114096 | 0.78 | ALDH1A1 (0.60) | ALDH1A1MAPTKMT2ANLRP1RAB9A | |
| SCHEMBL4111082 | 0.77 | MAPT (0.63) | ALDH1A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8104603 | 0.75 | MCHR1 (0.46) | ALDH1A1MAPTKMT2ANLRP1SMN1; SMN2 | |
| SCHEMBL8119058 | 0.74 | MCHR1 (0.45) | ALDH1A1MAPTKMT2ANLRP1SMN1; SMN2 | |
| SCHEMBL8113921 | 0.74 | RORC (0.46) | ALDH1A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8112799 | 0.74 | PSMB5 (0.47) | ALDH1A1MAPTKMT2ANLRP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |