Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113537 | 0.86 | ALDH1A1 (0.48) | MCHR1ALDH1A1MAPTHTTLMNA | |
| SCHEMBL8104603 | 0.85 | MCHR1 (0.46) | MCHR1ALDH1A1MAPTHTTPSMB5 | |
| SCHEMBL8119058 | 0.84 | MCHR1 (0.45) | MCHR1ALDH1A1MAPTHTTPSMB5 | |
| SCHEMBL8113921 | 0.84 | RORC (0.46) | MCHR1ALDH1A1MAPTPSMB5LMNA | |
| SCHEMBL8112799 | 0.83 | PSMB5 (0.47) | MCHR1ALDH1A1MAPTHTTPSMB5 | |
| SCHEMBL8114583 | 0.83 | MCHR1 (0.44) | MCHR1ALDH1A1MAPTHTTPSMB5 | |
| SCHEMBL8115072 | 0.80 | PLAU (0.43) | MCHR1ALDH1A1MAPTHTTPSMB5 | |
| Hydrochloric Acid SCHEMBL8120596 | 0.79 | PRSS1 (0.48) | ALDH1A1MAPTLMNAKMT2ATP53 | |
| SCHEMBL8119981 | 0.79 | ALDH1A1 (0.62) | MCHR1ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL8118516 | 0.78 | GPR34 (0.47) | ALDH1A1MAPTHTTPSMB5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |