Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.39 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.39 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.39 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | HAT1 | O14929 | 2/20 | 0.39 |
| ▸ | EP300 | Q09472 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126974 | 0.95 | ASAH1 (0.41) | ITGB3ITGA2BKMT2ACNR1CNR2 | |
| SCHEMBL8122078 | 0.92 | CASR (0.44) | ITGB3ITGA2BTDP1CNR1CNR2 | |
| SCHEMBL8127573 | 0.91 | MTNR1A (0.42) | KMT2AHAT1EP300 | |
| SCHEMBL8120771 | 0.89 | NPY1R (0.44) | CNR1CNR2 | |
| SCHEMBL8129753 | 0.85 | BCHE (0.40) | KDM4ESMN1; SMN2TDP1CASRALDH1A1 | |
| SCHEMBL4651833 | 0.84 | CNR1 (0.47) | KMT2AKDM4EGAASMN1; SMN2TDP1 | |
| SCHEMBL8112524 | 0.82 | KMT2A (0.47) | KMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL8127804 | 0.82 | GAA (0.41) | KMT2AKDM4EGAASMN1; SMN2MEN1 | |
| SCHEMBL8119335 | 0.82 | TRPV1 (0.41) | KMT2AGAAMEN1BLM | |
| SCHEMBL8529501 | 0.81 | NPY1R (0.38) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |