Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120019 | 0.95 | ITGB3 (0.41) | ITGB3ITGA2BHDAC1HDAC7ALDH1A1 | |
| SCHEMBL8122078 | 0.91 | CASR (0.44) | ITGB3ITGA2BHDAC1HDAC7ALDH1A1 | |
| SCHEMBL8127573 | 0.86 | MTNR1A (0.42) | KMT2A | |
| SCHEMBL8120771 | 0.84 | NPY1R (0.44) | CNR1CNR2 | |
| SCHEMBL8129753 | 0.83 | BCHE (0.40) | ALDH1A1 | |
| SCHEMBL8112524 | 0.80 | KMT2A (0.47) | ALDH1A1KMT2A | |
| SCHEMBL8127804 | 0.80 | GAA (0.41) | ALDH1A1KMT2A | |
| SCHEMBL8119335 | 0.80 | TRPV1 (0.41) | KMT2A | |
| SCHEMBL8529501 | 0.80 | NPY1R (0.38) | CNR1CNR2 | |
| SCHEMBL4651833 | 0.79 | CNR1 (0.47) | HDAC1HDAC7ALDH1A1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |