Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | EPOR | P19235 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112776 | 0.90 | EPOR (0.41) | CNR1CNR2EPORALDH1A1TDP1 | |
| SCHEMBL8126683 | 0.88 | EPOR (0.41) | CNR1CNR2EPORTDP1 | |
| SCHEMBL8127789 | 0.87 | TDP1 (0.46) | CNR1CNR2EPORALDH1A1TDP1 | |
| SCHEMBL8114831 | 0.82 | EPOR (0.39) | CNR1CNR2EPORALDH1A1TDP1 | |
| SCHEMBL7039253 | 0.80 | CASR (0.38) | CNR1CNR2ALDH1A1CASRKMT2A | |
| Hydrochloric Acid SCHEMBL8123089 | 0.80 | TDP1 (0.46) | CNR1CNR2ALDH1A1TDP1NPSR1 | |
| SCHEMBL8121285 | 0.79 | EPOR (0.41) | EPORKMT2A | |
| SCHEMBL9196992 | 0.79 | CNR1 (0.42) | CNR1CNR2ALDH1A1TDP1NPSR1 | |
| Trifluoroacetic Acid SCHEMBL8121476 | 0.79 | EPOR (0.45) | EPORALDH1A1TDP1NR1H3TAS2R14 | |
| SCHEMBL8120634 | 0.78 | PRSS1 (0.37) | EPORALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |