Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069677 | 0.92 | CNR1 (0.42) | CNR1CNR2ITGB3ITGA2BALDH1A1 | |
| SCHEMBL8069354 | 0.92 | CASR (0.45) | CNR1CNR2ALDH1A1KMT2AHDAC1 | |
| SCHEMBL9194821 | 0.91 | ALDH1A1 (0.42) | CNR1CNR2ITGB3ITGA2BALDH1A1 | |
| SCHEMBL8058871 | 0.91 | ALDH1A1 (0.42) | CNR1CNR2ITGB3ITGA2BALDH1A1 | |
| SCHEMBL9194825 | 0.91 | ALDH1A1 (0.42) | CNR1CNR2ITGB3ITGA2BALDH1A1 | |
| SCHEMBL8119013 | 0.91 | CNR1 (0.45) | CNR1CNR2KMT2A | |
| SCHEMBL9196147 | 0.86 | ALDH1A1 (0.43) | CNR1CNR2ITGB3ITGA2BALDH1A1 | |
| SCHEMBL9196151 | 0.86 | ALDH1A1 (0.43) | CNR1CNR2ITGB3ITGA2BALDH1A1 | |
| SCHEMBL8526883 | 0.84 | NPY1R (0.34) | ITGB3ITGA2B | |
| SCHEMBL7039253 | 0.83 | CASR (0.38) | CNR1CNR2ITGB3ITGA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |