Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 14/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.52 |
| ▸ | F2 | P00734 | 3/20 | 0.52 |
| ▸ | C1S | P09871 | 2/20 | 0.52 |
| ▸ | PLG | P00747 | 2/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | F12 | P00748 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7136929 | 0.82 | PARP1 (0.55) | — | |
| SCHEMBL4687380 | 0.80 | WDR5 (0.56) | PRSS1PRSS2PRSS3F2F10 | |
| SCHEMBL9608570 | 0.80 | PRSS1 (0.53) | PRSS1PRSS2PRSS3F2C1S | |
| SCHEMBL4680426 | 0.79 | FURIN (0.44) | F10 | |
| Hydrochloric Acid SCHEMBL2869263 | 0.78 | PRSS1 (0.55) | PRSS1PRSS2PRSS3F2C1S | |
| SCHEMBL18574572 | 0.78 | ASIC3 (0.70) | PRSS1PRSS2PRSS3F2C1S | |
| SCHEMBL15547311 | 0.78 | PRSS1 (0.70) | PRSS1PRSS2PRSS3F2C1S | |
| SCHEMBL1679846 | 0.78 | GSK3B (0.41) | PKM | |
| Hydrochloric Acid SCHEMBL28555629 | 0.75 | PRSS1 (0.74) | PRSS1PRSS2PRSS3F2C1S | |
| Hydrochloric Acid SCHEMBL28253026 | 0.75 | PRSS1 (0.74) | PRSS1PRSS2PRSS3F2C1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009758-A1 | META-BENZAMIDINE DERIVATIVES AS SERINE PROTEASE INHIBITORS | Protherics Molecular Design Limited (GB) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999011658-A1 | META-BENZAMIDINE DERIVATIVES AS SERIN PROTEASE INHIBITORS | PROTEUS MOLECULAR DESIGN LTD. (GB) | 1999-03-11 | — | — | WO | disclosed |