SCHEMBL9608570

SCHEMBL9608570

N#Cc1cccc(C(=N)N)c1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 14/20 0.53
PRSS2 P07478 6/20 0.53
PRSS3 P35030 6/20 0.53
C1S P09871 3/20 0.53
F2 P00734 2/20 0.53
PLG P00747 2/20 0.53
GSK3B P49841 2/20 0.51
LOXL2 Q9Y4K0 1/20 0.48
RECQL P46063 1/20 0.48
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2869263 0.98 PRSS1 (0.55) PRSS1PRSS2PRSS3C1SF2
Isopropyl Alcohol SCHEMBL28326201 0.90 PRSS1 (0.47) PRSS1PRSS2PRSS3C1SF2
Benzamidine SCHEMBL27541129 0.83 PRSS1 (0.53) PRSS1PRSS2PRSS3C1SF2
Phenyl Ethanol SCHEMBL28326106 0.82 PRSS1 (0.46) PRSS1PRSS2PRSS3C1SF2
Hydrochloric Acid SCHEMBL28325039 0.82 GSK3B (0.48) PRSS1PRSS2PRSS3C1SF2
Benzamidine SCHEMBL6823484 0.82 PRSS1 (0.68) PRSS1PRSS2PRSS3C1SF2
Hydrochloric Acid SCHEMBL28326094 0.81 PRSS1 (0.40) PRSS1PRSS2PRSS3C1SF2
SCHEMBL26050098 0.80 WDR5 (0.56) PRSS1PRSS2PRSS3F2PLG
SCHEMBL29858580 0.80 GSK3B (0.51) PRSS1GSK3B
SCHEMBL2041048 0.80 GSK3B (0.61) GSK3BRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250011315-A1 ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF PRISM MEDICINES, INC. 2025-01-09 US disclosed
US-12030876-B2 Aryl hydrocarbon receptor (AHR) agonists and uses thereof Ikena Oncology, Inc. (US) 2024-07-09 US disclosed
US-12030876-B2 Aryl hydrocarbon receptor (AHR) agonists and uses thereof Ikena Oncology, Inc. (US) 2024-07-09 US disclosed
US-20230295147-A1 ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF ARYL THERAPEUTICS, INC. 2023-09-21 US disclosed
US-20230295147-A1 ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF ARYL THERAPEUTICS, INC. 2023-09-21 US disclosed
US-20230117034-A1 PYRAZOLOTRIAZINES BAYER AKTIENGESELLSCHAFT (DE) 2023-04-20 US disclosed
US-11608329-B2 Aryl hydrocarbon receptor (AHR) agonists and uses thereof Ikena Oncology, Inc. (US) 2023-03-21 US disclosed
CN-115279741-A 4-phenyl-N- (phenyl) thiazol-2-amine derivatives and related compounds as Aryl Hydrocarbon Receptor (AHR) agonists for the treatment of, for example, angiogenesis-related disorders or inflammatory disorders 医肯纳肿瘤学公司 2022-11-01 CN disclosed
EP-4073072-A1 PYRAZOLOTRIAZINES Bayer Aktiengesellschaft (DE) 2022-10-19 EP disclosed
CN-115023427-A Pyrazolotriazines 拜耳公司 2022-09-06 CN disclosed
WO-2016080791-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2016-05-26 WO disclosed
WO-2015178732-A1 MULTI-COMPONENT HOST MATERIAL AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2015-11-26 WO disclosed
WO-2015160224-A1 MULTI-COMPONENT HOST MATERIAL AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2015-10-22 WO disclosed
WO-2015156587-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2015-10-15 WO disclosed
US-8975314-B2 Triazine derivative and ultraviolet absorber FUJIFILM CORPORATION (JP) 2015-03-10 US disclosed
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-20140213703-A1 NEW TRIAZINE DERIVATIVE AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2014-07-31 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250011315-A1 ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF AHR, ARNT, HCAR1 PRSS1 3635/4885PRSS2 3834/4885PRSS3 3607/4885
US-11608329-B2 Aryl hydrocarbon receptor (AHR) agonists and uses thereof AHR, ARNT, HCAR1 PRSS1 3635/4885PRSS2 3834/4885PRSS3 3607/4885
US-20230117034-A1 PYRAZOLOTRIAZINES BRCA1, TPX2, CCND2 PRSS1 375/4885PRSS2 395/4885PRSS3 366/4885
US-12030876-B2 Aryl hydrocarbon receptor (AHR) agonists and uses thereof AHR, ARNT, HCAR1 PRSS1 3635/4885PRSS2 3834/4885PRSS3 3607/4885
US-20230295147-A1 ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF AHR, ARNT, HCAR1 PRSS1 3635/4885PRSS2 3834/4885PRSS3 3607/4885
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 PRSS1 2006/4885PRSS2 2119/4885PRSS3 1890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.