Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 20/20 | 0.68 |
| ▸ | CTSK | P43235 | 20/20 | 0.68 |
| ▸ | CTSS | P25774 | 16/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123168 | 0.84 | CTSB (0.68) | CTSBCTSKCTSSKCNH2 | |
| SCHEMBL8115758 | 0.81 | CTSK (1.00) | CTSBCTSKCTSSKCNH2 | |
| SCHEMBL8106379 | 0.77 | CTSK (0.76) | CTSBCTSKCTSSKCNH2 | |
| SCHEMBL4572944 | 0.76 | ALDH1A1 (0.39) | CTSBCTSKCTSSKCNH2 | |
| SCHEMBL4899778 | 0.76 | CTSK (0.89) | CTSBCTSKCTSSKCNH2 | |
| SCHEMBL4894615 | 0.76 | CTSK (0.87) | CTSBCTSKCTSSKCNH2 | |
| SCHEMBL8109515 | 0.74 | CTSB (0.65) | CTSBCTSKCTSSKCNH2 | |
| SCHEMBL8123336 | 0.73 | CTSK (0.71) | CTSBCTSKCTSSKCNH2 | |
| SCHEMBL8123357 | 0.73 | CTSK (0.67) | CTSBCTSKCTSSKCNH2 | |
| SCHEMBL8108841 | 0.73 | CTSB (0.76) | CTSBCTSKCTSSKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |