Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 6/20 | 0.35 |
| ▸ | NPY1R | P25929 | 6/20 | 0.35 |
| ▸ | NPY2R | P49146 | 4/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121919 | 0.82 | NPY1R (0.35) | NPY4RNPY1RNPY2RNPY5RMTOR | |
| SCHEMBL8126834 | 0.82 | CACNA1B (0.41) | NPY1RF2 | |
| SCHEMBL9271189 | 0.82 | NPY1R (0.37) | NPY1RMTORF2ADAM17 | |
| SCHEMBL8120885 | 0.81 | NPY1R (0.55) | NPY4RNPY1RNPY5R | |
| SCHEMBL8119387 | 0.81 | NPY1R (0.45) | NPY4RNPY1RNPY2RNPY5RNOS1 | |
| SCHEMBL8121207 | 0.81 | NPY1R (0.35) | NPY4RNPY1RNPY2RNPY5RF2 | |
| SCHEMBL8120806 | 0.77 | ADAM17 (0.36) | NPY4RNPY1RNPY2RNPY5RF2 | |
| SCHEMBL8119391 | 0.74 | NPY1R (0.43) | NPY4RNPY1RNPY2RNPY5RF2 | |
| SCHEMBL8112864 | 0.74 | F2 (0.36) | NPY1RF2ADAM17 | |
| SCHEMBL8124247 | 0.74 | NPY1R (0.42) | NPY4RNPY1RNPY5RF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |