Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | BRS3 | P32247 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | ATP1A1 | P05023 | 5/20 | 0.43 |
| ▸ | ATP1B1 | P05026 | 5/20 | 0.43 |
| ▸ | ATP1A3 | P13637 | 5/20 | 0.43 |
| ▸ | ATP1B2 | P14415 | 5/20 | 0.43 |
| ▸ | ATP4A | P20648 | 5/20 | 0.43 |
| ▸ | ATP1A2 | P50993 | 5/20 | 0.43 |
| ▸ | ATP4B | P51164 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122272 | 0.91 | CYP2D6 (0.58) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29527371 | 0.90 | RAB9A (0.59) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL26639245 | 0.90 | RAB9A (0.59) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8133873 | 0.89 | CYP1A2 (0.55) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10336030 | 0.88 | CYP2D6 (0.56) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10713337 | 0.88 | BRS3 (0.57) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29527281 | 0.88 | RAB9A (0.76) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL26639266 | 0.88 | RAB9A (0.76) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2383094 | 0.87 | CYP1A2 (0.55) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29527279 | 0.87 | CYP2D6 (0.61) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357261-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | The University of Pittsburgh- of the Commonwealth System of Higher Education | 2023-11-09 | — | — | US | disclosed |
| US-20230357261-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | The University of Pittsburgh- of the Commonwealth System of Higher Education | 2023-11-09 | — | — | US | disclosed |
| US-20230357261-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | The University of Pittsburgh- of the Commonwealth System of Higher Education | 2023-11-09 | — | — | US | disclosed |
| WO-2022061140-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2022-03-24 | — | — | WO | disclosed |
| EP-0481764-B1 | Pyridine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-03-29 | — | — | EP | disclosed |
| US-5312824-A | Certain 2-[(4-difluoromethoxy-2-pyridyl)-methylthio or methylsulfinyl-5-benzimidazoles useful for treating peptic ulcers | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0481764-A1 | Pyridine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-04-22 | — | — | EP | disclosed |
| US-4950677-A | ANTIULCER AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1990-08-21 | — | — | US | disclosed |
| EP-0304624-A2 | Benzimidazol-2-yl-pyridinum compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1989-03-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357261-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | AHR, ARNT, MTNR1A | RAB9A 4548/4885NPC1 2517/4885CYP1A2 237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.