Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14760449 | 0.79 | KMT2A (0.48) | KDM4EMAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL7038577 | 0.77 | MAPT (0.53) | MDM2KDM4ESMN1; SMN2MAPTKMT2A | |
| SCHEMBL9277706 | 0.76 | KMT2A (0.46) | KDM4EMAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL18708623 | 0.75 | EED (0.47) | KDM4ESMN1; SMN2KMT2AMEN1L3MBTL1 | |
| SCHEMBL8895528 | 0.74 | GRIN2D (0.48) | MDM2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL2585402 | 0.74 | MEN1 (0.47) | KDM4EKMT2AMEN1L3MBTL1PDE3B | |
| Hydrochloric Acid SCHEMBL2591808 | 0.72 | MEN1 (0.46) | KDM4EKMT2AMEN1L3MBTL1PDE3B | |
| SCHEMBL2591527 | 0.72 | KDM4E (0.58) | KDM4EMAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL27634125 | 0.72 | ALDH1A1 (0.60) | SMN1; SMN2MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL9697271 | 0.71 | BCL2 (0.45) | SMN1; SMN2MAPTKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019376-A1 | PYRIDONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS SYNTHESIS INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998031671-A1 | PYRIDONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS SYNTHESIS INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 1998-07-23 | — | — | WO | disclosed |