Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14760449 | 0.78 | KMT2A (0.48) | BCL2BCL2L1PDE3BPDE3AMAPT | |
| SCHEMBL9277706 | 0.75 | KMT2A (0.46) | BCL2BCL2L1PDE3BPDE3AMAPT | |
| SCHEMBL7296501 | 0.74 | TSHR (0.61) | PDE3BPDE3ASMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL9454876 | 0.74 | PTGS2 (0.44) | MAPTALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL18708623 | 0.74 | EED (0.47) | PDE3BPDE3ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL10771506 | 0.74 | PDE3B (0.46) | BCL2BCL2L1PDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL2585402 | 0.73 | MEN1 (0.47) | PDE3BPDE3AALDH1A1KMT2AMEN1 | |
| SCHEMBL2591527 | 0.72 | KDM4E (0.58) | PDE3BPDE3AMAPTCYP3A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2591808 | 0.72 | MEN1 (0.46) | PDE3BPDE3AALDH1A1KMT2AMEN1 | |
| SCHEMBL8092285 | 0.72 | BCL2 (0.54) | BCL2BCL2L1CALM1ALOX5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500824-A1 | POLYMERS FOR SCAVENGING NITROSATING AGENTS | CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1992-09-02 | — | — | EP | disclosed |
| WO-1992000122-A1 | POLYMERS FOR SCAVENGING NITROSATING AGENTS | CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1992-01-09 | — | — | WO | disclosed |