Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 2/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.35 |
| ▸ | CHRNG | P07510 | 2/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.35 |
| ▸ | CHRND | Q07001 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | EPOR | P19235 | 5/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8125989 | 0.96 | NPY1R (0.37) | TRPV1NPY1RCHRNA1CHRNGCHRNB1 | |
| SCHEMBL8114061 | 0.90 | PLAAT3 (0.41) | TRPV1NPY1RF2NPY2RNPY5R | |
| SCHEMBL8122024 | 0.90 | HDAC3 (0.41) | TRPV1F2PLGPRSS1 | |
| SCHEMBL8112667 | 0.89 | HDAC3 (0.42) | TRPV1F2EPORPLGPRSS1 | |
| SCHEMBL8127301 | 0.88 | MEN1 (0.33) | CA1CA2 | |
| SCHEMBL8124247 | 0.86 | NPY1R (0.42) | NPY1RF2NPY5R | |
| SCHEMBL8121207 | 0.86 | NPY1R (0.35) | NPY1RF2NPY2RNPY5RGRIA1 | |
| SCHEMBL8125832 | 0.86 | F2 (0.36) | TRPV1NPY1RF2EPOR | |
| SCHEMBL8114448 | 0.85 | NPY1R (0.39) | TRPV1NPY1RCHRNA1CHRNGCHRNB1 | |
| SCHEMBL8126150 | 0.85 | F2 (0.35) | NPY1RF2EPOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |