Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 4/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.34 |
| ▸ | CHRNG | P07510 | 3/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.34 |
| ▸ | CHRND | Q07001 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123419 | 0.96 | TRPV1 (0.37) | NPY1RNPY2RNPY5RF2CHRNA1 | |
| SCHEMBL8114061 | 0.86 | PLAAT3 (0.41) | NPY1RNPY2RNPY5RF2HDAC3 | |
| SCHEMBL8122024 | 0.85 | HDAC3 (0.41) | F2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8127301 | 0.85 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL8112667 | 0.85 | HDAC3 (0.42) | F2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8124247 | 0.84 | NPY1R (0.42) | NPY1RNPY5RF2 | |
| SCHEMBL8120508 | 0.84 | F2 (0.38) | NPY1RNPY5RF2HDAC3HDAC4 | |
| SCHEMBL8121207 | 0.84 | NPY1R (0.35) | NPY1RNPY2RNPY5RF2GRIA1 | |
| SCHEMBL8125832 | 0.83 | F2 (0.36) | NPY1RF2TRPV1 | |
| SCHEMBL8114448 | 0.83 | NPY1R (0.39) | NPY1RNPY2RNPY5RF2CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |