SCHEMBL812405

SCHEMBL812405

C=COC(=O)NCCC[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACHE P22303 8/20 0.33
EPHX1 P07099 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35590 0.87 ACHE (0.33) ACHEEPHX1ZDHHC20ZDHHC2
SCHEMBL810665 0.87 ACHE (0.33) ACHEEPHX1ZDHHC20ZDHHC2
SCHEMBL5685623 0.86 ACHE (0.33) ACHEEPHX1ZDHHC20ZDHHC2
SCHEMBL1286118 0.81 ACHE (0.38) ACHE
SCHEMBL13288287 0.80
SCHEMBL1285506 0.80 ZDHHC20 (0.51) ZDHHC20ZDHHC2
SCHEMBL7023232 0.79 ERN1 (0.34) ACHE
SCHEMBL20608972 0.77 EPHX1 (0.38) ACHEEPHX1ZDHHC20ZDHHC2
SCHEMBL16070995 0.77 EPHX1 (0.38) ACHEEPHX1ZDHHC20ZDHHC2
SCHEMBL28396215 0.75 ACHE (0.57) ACHEEPHX1ZDHHC20ZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240010777-A1 SURFACE TREATMENT AGENT FOR OPHTHALMIC DEVICE NOF CORPORATION (JP) 2024-01-11 US disclosed
EP-4258042-A1 SURFACE TREATMENT AGENT FOR OPHTHALMIC DEVICE NOF Corporation (JP) 2023-10-11 EP disclosed
US-10941311-B2 Polyoxyethylene compound having multiple hydroxyl groups at end, and contact lens NOF CORPORATION (JP) 2021-03-09 US disclosed
US-10745518-B2 Branching-type polyoxyethylene compound and contact lens NOF CORPORATION (JP) 2020-08-18 US disclosed
US-20190136085-A1 POLYOXYETHYLENE COMPOUND HAVING MULTIPLE HYDROXYL GROUPS AT END, AND CONTACT LENS NOF CORPORATION (JP) 2019-05-09 US disclosed
US-20190106539-A1 BRANCHING-TYPE POLYOXYETHYLENE COMPOUND AND CONTACT LENS NOF CORPORATION (JP) 2019-04-11 US disclosed
US-20180314077-A1 DRUG SUSTAINED-RELEASING MEDICAL CONTACT LENS NOF CORPORATION (JP) 2018-11-01 US disclosed
EP-2625218-B1 WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF NOVARTIS AG (CH) 2018-04-25 EP disclosed
US-9921340-B2 Water-processable silicone-containing prepolymers and uses thereof NOVARTIS AG (CH) 2018-03-20 US disclosed
US-20160033683-A1 WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF ALCON INC. (CH) 2016-02-04 US disclosed
US-9187601-B2 Water-processable silicone-containing prepolymers and uses thereof NOVARTIS AG (CH) 2015-11-17 US disclosed
EP-2388281-B1 SILICONE MONOMER NOF CORP (JP) 2013-11-06 EP disclosed
EP-2625218-A1 WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF Novartis AG (CH) 2013-08-14 EP disclosed
US-20120088861-A1 WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF ALCON INC. (CH) 2012-04-12 US disclosed
WO-2012047969-A1 WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF NOVARTIS AG (CH) 2012-04-12 WO disclosed
EP-2388281-A1 SILICONE MONOMER NOF Corporation (JP) 2011-11-23 EP disclosed
US-8040078-B1 LED dimming circuit KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2011-10-18 US disclosed