Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 8/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35366 | 0.93 | ACHE (0.38) | ERN1BRD4ACHEHRH4HRH3 | |
| SCHEMBL35590 | 0.90 | ACHE (0.33) | ACHE | |
| SCHEMBL1286118 | 0.82 | ACHE (0.38) | ERN1BRD4ACHEHRH4HRH3 | |
| SCHEMBL13288287 | 0.81 | — | — | |
| SCHEMBL812405 | 0.79 | ACHE (0.33) | ACHE | |
| SCHEMBL810665 | 0.79 | ACHE (0.33) | ACHE | |
| SCHEMBL7090002 | 0.79 | BRD4 (0.42) | ERN1BRD4ACHEHRH4HRH3 | |
| SCHEMBL8679303 | 0.78 | — | — | |
| SCHEMBL8763776 | 0.77 | ACHE (0.46) | ACHEHRH4HRH3TSHR | |
| SCHEMBL20608972 | 0.75 | EPHX1 (0.38) | ACHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019416-B1 | LOW WATER POLYMERIC SILICONE COMPOSITIONS HAVING REDUCED MODULUS | BAUSCH & LOMB (US) | 2003-01-22 | — | — | EP | disclosed |
| EP-1019416-A1 | MONOMERIC UNITS USEFUL FOR REDUCING THE MODULUS OF LOW WATER POLYMERIC SILICONE COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1997020851-A1 | MONOMERIC UNITS USEFUL FOR REDUCING THE MODULUS OF LOW WATER POLYMERIC SILICONE COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 1997-06-12 | — | — | WO | disclosed |