Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8118285 | 0.85 | ALDH1A1 (0.38) | EGLN2ALDH1A1LMNAENPP1KDM4E | |
| SCHEMBL8124935 | 0.85 | EGLN2 (0.44) | EGLN2ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL8118491 | 0.82 | KMT2A (0.41) | ALDH1A1LMNAKDM4ESMN1; SMN2POLB | |
| SCHEMBL868326 | 0.81 | KDM4E (0.49) | EGLN2ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5420498 | 0.80 | KMT2A (0.47) | EGLN2ALDH1A1KDM4EPDE2APOLB | |
| SCHEMBL4998515 | 0.80 | KMT2A (0.44) | ALDH1A1KDM4EPDE2APOLBMAPK1 | |
| SCHEMBL8916382 | 0.80 | LMNA (0.41) | EGLN2ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL8117996 | 0.79 | KDM4E (0.47) | EGLN2ALDH1A1LMNAENPP1KDM4E | |
| SCHEMBL5236413 | 0.78 | ALDH1A1 (0.40) | EGLN2ALDH1A1LMNAENPP1SMN1; SMN2 | |
| SCHEMBL6993136 | 0.78 | ALDH1A1 (0.43) | EGLN2ALDH1A1ENPP1PDE2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782997-B1 | Triazolopyrimidine derivatives | SHELL INT RESEARCH (NL) | 2000-04-26 | — | — | EP | claimed |
| EP-0782997-A2 | Triazolopyrimidine derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1997-07-09 | — | — | EP | claimed |
| EP-0782997-B1 | Triazolopyrimidine derivatives | SHELL INT RESEARCH (NL) | 2000-04-26 | — | — | EP | disclosed |
| EP-0699200-B1 | DIHALOTRIAZOLOPYRIMIDINE DERIVATIVES AS FUNGICIDES | SHELL INT RESEARCH (NL) | 1997-10-29 | — | — | EP | disclosed |
| US-5612345-A | Dihalotriazolopyrimidine derivatives as fungicides | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1997-03-18 | — | — | US | disclosed |