Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119583 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ANPSR1USP2 | |
| SCHEMBL8126427 | 0.80 | CYP3A4 (0.47) | ALDH1A1MEN1KMT2ANPSR1USP2 | |
| SCHEMBL8125197 | 0.78 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ATSHRNPSR1 | |
| SCHEMBL7951448 | 0.78 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ATSHRNPSR1 | |
| SCHEMBL11431397 | 0.78 | ALDH1A1 (0.36) | ALDH1A1KMT2ANPSR1CYP3A4HTT | |
| SCHEMBL8129633 | 0.74 | LMNA (0.44) | ALDH1A1MEN1KMT2ATSHRUSP2 | |
| SCHEMBL7649121 | 0.74 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ATSHRNPSR1 | |
| SCHEMBL8127530 | 0.74 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ATSHRNPSR1 | |
| SCHEMBL8133210 | 0.73 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ANPSR1USP2 | |
| SCHEMBL7655761 | 0.71 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6160114-A | USEFUL FOR THE TREATMENT OF ATHEROSCLEROTIC CONDITIONS AND CORONARY HEART DISEASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-12-12 | — | — | US | disclosed |