Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | FBP1 | P09467 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8118065 | 0.90 | FBP1 (0.47) | C1RPRSS1FBP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8124695 | 0.87 | FBP1 (0.46) | C1RPRSS1FBP1SMN1; SMN2PTPN2 | |
| SCHEMBL8119287 | 0.84 | C1R (0.49) | C1RPRSS1FBP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8118398 | 0.82 | C1R (0.49) | C1RPRSS1FBP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8119484 | 0.81 | C1R (0.53) | C1RPRSS1FBP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8117368 | 0.80 | TP53 (0.44) | C1RPRSS1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8117758 | 0.79 | C1R (0.48) | C1RPRSS1FBP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8119897 | 0.78 | FBP1 (0.49) | FBP1SMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL4905642 | 0.77 | C1R (0.49) | C1RPRSS1FBP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4898294 | 0.77 | C1R (0.49) | C1RPRSS1FBP1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036069-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999028306-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | disclosed |