Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 5/20 | 0.46 |
| ▸ | PTPN22 | Q9Y2R2 | 6/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | C1R | P00736 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119897 | 0.91 | FBP1 (0.49) | FBP1PTPN22CASP3SMN1; SMN2SENP7 | |
| SCHEMBL8117800 | 0.87 | SMN1; SMN2 (0.52) | FBP1PTPN22CASP3SMN1; SMN2SENP7 | |
| SCHEMBL8124274 | 0.87 | C1R (0.49) | FBP1CASP3SMN1; SMN2SENP7SENP6 | |
| SCHEMBL8118219 | 0.85 | PTPN22 (0.47) | FBP1PTPN22CASP3SMN1; SMN2SENP7 | |
| SCHEMBL8125216 | 0.85 | FBP1 (0.45) | FBP1PTPN22CASP3SMN1; SMN2SENP7 | |
| SCHEMBL8119027 | 0.84 | PTPN22 (0.45) | FBP1PTPN22CASP3SMN1; SMN2SENP7 | |
| SCHEMBL8133971 | 0.81 | ALDH1A1 (0.51) | SMN1; SMN2PKMTRPM8 | |
| SCHEMBL8124178 | 0.80 | PTPN22 (0.44) | FBP1PTPN22C1RPRSS1PTPN1 | |
| SCHEMBL8120344 | 0.80 | PTPN22 (0.46) | FBP1PTPN22CASP3SMN1; SMN2SENP7 | |
| SCHEMBL8118065 | 0.79 | FBP1 (0.47) | FBP1CASP3SMN1; SMN2SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036069-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999028306-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | disclosed |