Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | FBP1 | P09467 | 6/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124178 | 0.89 | PTPN22 (0.44) | C1RPRSS1FBP1CNR1CNR2 | |
| SCHEMBL8109538 | 0.87 | PRSS1 (0.52) | C1RPRSS1FBP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8123575 | 0.85 | FBP1 (0.43) | C1RPRSS1FBP1KDM4EALDH1A1 | |
| SCHEMBL8119287 | 0.83 | C1R (0.49) | C1RPRSS1FBP1KDM4EALDH1A1 | |
| SCHEMBL8124274 | 0.79 | C1R (0.49) | C1RPRSS1FBP1KDM4EALDH1A1 | |
| SCHEMBL8118398 | 0.79 | C1R (0.49) | C1RPRSS1FBP1KDM4EALDH1A1 | |
| SCHEMBL8120344 | 0.78 | PTPN22 (0.46) | C1RPRSS1FBP1SMN1; SMN2PTPN22 | |
| SCHEMBL8119484 | 0.78 | C1R (0.53) | C1RPRSS1FBP1KDM4EALDH1A1 | |
| SCHEMBL8110017 | 0.78 | FBP1 (0.68) | FBP1 | |
| SCHEMBL4898294 | 0.75 | C1R (0.49) | C1RPRSS1FBP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036069-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999028306-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | disclosed |