Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119111 | 0.84 | BCHE (0.48) | BCHEACHEALDH1A1BRD4CARM1 | |
| SCHEMBL8119499 | 0.84 | BCHE (0.46) | BCHEACHEKMT2AMEN1ALDH1A1 | |
| SCHEMBL8124392 | 0.81 | BCHE (0.45) | BCHEACHEKMT2AMEN1ALDH1A1 | |
| SCHEMBL8131620 | 0.81 | ACHE (0.49) | BCHEACHEHTR1AHTR2ABRD4 | |
| SCHEMBL8130052 | 0.80 | ACHE (0.50) | BCHEACHEKMT2AMEN1ALDH1A1 | |
| SCHEMBL8129042 | 0.79 | BCHE (0.45) | BCHEACHEKMT2AMEN1ALDH1A1 | |
| SCHEMBL8129045 | 0.79 | BCHE (0.45) | BCHEACHEKMT2AMEN1ALDH1A1 | |
| SCHEMBL8129271 | 0.79 | ACHE (0.47) | BCHEACHEHTR1A | |
| SCHEMBL8132943 | 0.75 | BCHE (0.49) | BCHEACHEKMT2AMEN1ALDH1A1 | |
| SCHEMBL8132940 | 0.75 | BCHE (0.49) | BCHEACHEKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610134-B1 | Indole derivatives as 5-HT1-like agonists | ADIR (FR) | 2000-04-05 | — | — | EP | disclosed |
| US-5348968-A | Migraines | ADIR ET COMPAGNIE (FR) | 1994-09-20 | — | — | US | disclosed |
| EP-0610134-A1 | Indole, indazole and benzisoxazole derivatives as 5-HT1-like agonists | ADIR ET COMPAGNIE (FR) | 1994-08-10 | — | — | EP | disclosed |