Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.45 |
| ▸ | ACHE | P22303 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCH | P24723 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8129045 | 1.00 | BCHE (0.45) | BCHEACHEKMT2AMEN1USP2 | |
| SCHEMBL8132943 | 0.86 | BCHE (0.49) | BCHEACHEKMT2AMEN1USP2 | |
| SCHEMBL8132940 | 0.86 | BCHE (0.49) | BCHEACHEKMT2AMEN1USP2 | |
| SCHEMBL8133152 | 0.82 | HTR2A (0.48) | BCHEACHEMAOAMAOBDRD2 | |
| SCHEMBL8133156 | 0.82 | HTR2A (0.48) | BCHEACHEMAOAMAOBDRD2 | |
| SCHEMBL8119499 | 0.82 | BCHE (0.46) | BCHEACHEKMT2AMEN1USP2 | |
| SCHEMBL8119111 | 0.80 | BCHE (0.48) | BCHEACHEALDH1A1PRKCGPRKCB | |
| SCHEMBL8124392 | 0.79 | BCHE (0.45) | BCHEACHEKMT2AMEN1USP2 | |
| SCHEMBL8124394 | 0.79 | BCHE (0.51) | BCHEACHEKMT2AMEN1USP2 | |
| SCHEMBL8131620 | 0.79 | ACHE (0.49) | BCHEACHEPRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610134-B1 | Indole derivatives as 5-HT1-like agonists | ADIR (FR) | 2000-04-05 | — | — | EP | disclosed |
| US-5348968-A | Migraines | ADIR ET COMPAGNIE (FR) | 1994-09-20 | — | — | US | disclosed |
| EP-0610134-A1 | Indole, indazole and benzisoxazole derivatives as 5-HT1-like agonists | ADIR ET COMPAGNIE (FR) | 1994-08-10 | — | — | EP | disclosed |