SCHEMBL812451

SCHEMBL812451

Cc1ccc(C)c2ncccc12

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.70
PSMD14 O00487 2/20 0.70
COPS5 Q92905 2/20 0.70
SLC6A2 P23975 1/20 0.70
L3MBTL1 Q9Y468 2/20 0.60
HSP90AA1 P07900 2/20 0.60
NPC1 O15118 1/20 0.60
SMN1; SMN2 Q16637 2/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
CCR1 P32246 4/20 0.59
CCR8 P51685 4/20 0.59
CCR5 P51681 3/20 0.57
LMNA P02545 3/20 0.50
SLC40A1 Q9NP59 1/20 0.50
HTR1A P08908 1/20 0.48
ADRA1D P25100 1/20 0.48
ADRA1A P35348 1/20 0.48
ADRA1B P35368 1/20 0.48
CYP1A2 P05177 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2607397 0.84 PSMD14 (0.68) HTTPSMD14COPS5SLC6A2L3MBTL1
Tiliquinol SCHEMBL145245 0.83 HTT (1.00) HTTPSMD14COPS5SLC6A2L3MBTL1
SCHEMBL21130214 0.83 PSMD14 (0.72) HTTPSMD14COPS5SLC6A2L3MBTL1
SCHEMBL13977568 0.83 PSMD14 (1.00) HTTPSMD14COPS5SLC6A2L3MBTL1
SCHEMBL2056205 0.83 KDM4E (0.61) HTTPSMD14COPS5SLC6A2L3MBTL1
SCHEMBL12332383 0.83 MEN1 (0.53) HTTPSMD14COPS5SLC6A2L3MBTL1
SCHEMBL6019580 0.83 MEN1 (0.53) HTTPSMD14COPS5SLC6A2L3MBTL1
SCHEMBL5545027 0.83 HTT (0.61) HTTPSMD14COPS5SLC6A2L3MBTL1
SCHEMBL3717647 0.83 PSMD14 (0.61) HTTPSMD14COPS5SLC6A2L3MBTL1
SCHEMBL5118047 0.83 HTT (0.61) HTTPSMD14COPS5SLC6A2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 512 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119340464-A Novel wide electrochemical window polymer solid electrolyte and preparation method thereof 浙江智邦锂电新材料有限公司 2025-01-21 CN claimed
CN-119340463-A Long-life wide electrochemical window polymer solid electrolyte and preparation method thereof 浙江智邦锂电新材料有限公司 2025-01-21 CN claimed
CN-118667065-A Self-supporting polymer solid electrolyte and preparation method thereof 浙江智邦锂电新材料有限公司 2024-09-20 CN claimed
US-9796800-B2 Process for producing polydienes BRIDGESTONE CORPORATION (JP) 2017-10-24 US claimed
US-20160108153-A1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTONE CORPORATION (JP) 2016-04-21 US claimed
CN-103154044-B Process for producing polydienes BRIDGESTONE CO.,LTD. (JP) 2016-02-17 CN claimed
US-9249244-B2 Process for producing polydienes BRIDGESTONE CORPORATION (JP) 2016-02-02 US claimed
EP-2619233-A1 PROCESS FOR PRODUCING POLYDIENES Bridgestone Corporation (JP) 2013-07-31 EP claimed
CN-103154044-A Process for producing polydienes BRIDGESTONE CORP 2013-06-12 CN claimed
WO-2012040026-A1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTONE CORPORATION (JP) 2012-03-29 WO claimed
US-20040106633-A1 Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors 3-DIMENSIONAL PHARMACEUTICALS, INC. 2004-06-03 US claimed
US-6706021-B2 ANTICOAGULANT FOR CATHETERS, DIALYSIS MACHINES, SYRINGES, TUBES, BLOOD LINES AND STENTS; TRYPSIN-LIKE SERINE PROTEASES SUCH AS THROMBIN; 3-BENZYLSULFONYLAMINO-6-METHYL-1-((2-GUANIDINOOXYETHYL) AMINOCARBONYLMETHYL)-2-PYRIDINONE 3-DIMENSIONAL PHARMACEUTICALS, INC. 2004-03-16 US claimed
US-20030225115-A1 Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors 3-DIMENSIONAL PHARMACEUTICALS, INC. 2003-12-04 US claimed
US-6566379-B1 As proteolytic enzyme inhibitors; thrombin inhibitors; for therapy of pancreatitis, thrombosis, ischemia, stroke, restenosis, emphysema or inflammation in a mammal 3-DIMENSIONAL PHARMACEUTICALS, INC. 2003-05-20 US claimed
US-20030087921-A1 Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors 3-DIMENSIONAL PHARMACEUTICALS, INC. 2003-05-08 US claimed
US-20020007070-A1 Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors LU TIANBAO (US) 2002-01-17 US claimed
US-6326492-B1 ANTICOAGULANT 3-DIMENSIONAL PHARMACEUTICALS, INC. 2001-12-04 US claimed
EP-1036063-A1 HETEROARYL AMINOGUANIDINES AND ALKOXYGUANIDINES AND THEIR USE AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2000-09-20 EP claimed
US-6037356-A ANTICOAGULANTS; ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2000-03-14 US claimed
WO-1999026926-A1 HETEROARYL AMINOGUANIDINES AND ALKOXYGUANIDINES AND THEIR USE AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 1999-06-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030225115-A1 Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors F9, PLG, F2R HTT 1042/4885PSMD14 2160/4885COPS5 2489/4885
US-20020007070-A1 Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors F9, PLG, PLAT HTT 1041/4885PSMD14 2049/4885COPS5 2374/4885
US-20030087921-A1 Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors F9, PLG, F2R HTT 1042/4885PSMD14 2160/4885COPS5 2489/4885
US-20040106633-A1 Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors F9, PLG, MMP9 HTT 1027/4885PSMD14 2135/4885COPS5 2541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.