Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8118751 | 0.83 | MTNR1A (0.42) | MTNR1AMTNR1BNPC1RAB9ATDP1 | |
| SCHEMBL8126457 | 0.83 | MTNR1A (0.53) | MTNR1AMTNR1BNPC1RAB9AKDM4E | |
| SCHEMBL8128784 | 0.82 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL8133947 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BNPC1RAB9AKDM4E | |
| SCHEMBL8125047 | 0.81 | MTNR1A (0.61) | MTNR1AMTNR1B | |
| SCHEMBL8127090 | 0.81 | ALDH1A1 (0.42) | MTNR1AMTNR1BNPC1RAB9ATDP1 | |
| SCHEMBL8127457 | 0.81 | MTNR1A (0.63) | MTNR1AMTNR1BNQO1 | |
| SCHEMBL8132270 | 0.81 | MTNR1A (0.61) | MTNR1AMTNR1BNPC1RAB9AKDM4E | |
| SCHEMBL8131508 | 0.80 | MTNR1A (0.42) | MTNR1AMTNR1BNPC1RAB9AKDM4E | |
| SCHEMBL8118628 | 0.78 | MTNR1A (0.44) | MTNR1AMTNR1BNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147110-A | MELATONINERGIC AGENTS; SLEEP, EATING, CENTRAL NERVOUS SYSTEM, AND CARDIOVASCULAR DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-11-14 | — | — | US | disclosed |
| EP-0926145-A1 | Napthalene compounds, method for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-06-30 | — | — | EP | disclosed |