Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8125726 | 0.89 | LTA4H (0.49) | LTA4HTSHRALDH1A1 | |
| SCHEMBL8480190 | 0.86 | LTA4H (0.44) | LTA4HTSHRMAOBHSD17B10ALDH1A1 | |
| SCHEMBL7675265 | 0.82 | LTA4H (0.50) | LTA4HMAOBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27518981 | 0.81 | LTA4H (0.47) | LTA4HTSHRMAOBHSD17B10ALDH1A1 | |
| SCHEMBL27628611 | 0.79 | MAOB (0.44) | LTA4HTSHRMAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL7400862 | 0.79 | DRD2 (0.35) | — | |
| SCHEMBL9627150 | 0.78 | LTA4H (0.35) | LTA4HTSHRHSD17B10ALDH1A1KDM4E | |
| SCHEMBL10368042 | 0.76 | LTA4H (0.35) | LTA4H | |
| SCHEMBL11098034 | 0.75 | LTA4H (0.39) | LTA4HTSHRMAOBALDH1A1KDM4E | |
| SCHEMBL27543978 | 0.74 | LTA4H (0.38) | LTA4HTSHRMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015434-A2 | NOVEL PYRIMIDIN-4-ONE AND PYRIMIDIN-4-THIONE AS FUNGICIDE | Novartis AG (CH) | 2000-07-05 | — | — | EP | disclosed |
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |
| WO-1999014202-A2 | NOVEL PYRIMIDIN-4-ONE AND PYRIMIDIN-4-THIONE AS FUNGICIDE | NOVARTIS AG (CH) | 1999-03-25 | — | — | WO | disclosed |