SCHEMBL81261

SCHEMBL81261

NC(=O)Oc1ccc(Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
KIF11 P52732 1/20 0.50
CYP1A2 P05177 2/20 0.49
ELANE P08246 1/20 0.47
LIPE Q05469 2/20 0.46
HPGD P15428 1/20 0.45
NPC1 O15118 2/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C19 P33261 1/20 0.44
PPARA Q07869 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
MAOA P21397 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29185988 0.90 MEN1 (0.44) MEN1KMT2AKIF11CYP1A2ELANE
SCHEMBL6284986 0.87 KMT2A (0.64) MEN1KMT2AKIF11ELANECA1
Toluene SCHEMBL28917433 0.85 LMNA (0.46) MEN1KMT2ACYP1A2ELANENPC1
SCHEMBL7063178 0.80 ELANE (0.50) MEN1KMT2ACYP1A2ELANELIPE
SCHEMBL56865 0.80 KMT2A (0.50) MEN1KMT2ACYP1A2ELANELIPE
SCHEMBL31366711 0.80 CYP2C9 (0.58) MEN1KMT2ACYP1A2HPGDNPC1
Guanidine SCHEMBL7467156 0.79 ELANE (0.46) MEN1KMT2ACYP1A2ELANELIPE
SCHEMBL59462 0.78 ELANE (0.48) MEN1KMT2ACYP1A2ELANELIPE
SCHEMBL1850368 0.78 KMT2A (0.54) MEN1KMT2AKIF11CYP3A4MAPT
SCHEMBL348122 0.78 MEN1 (0.54) MEN1KMT2AKIF11ELANEHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110940740-B Detection method of L-alpha-glycerophosphorylcholine isomer 江苏威奇达药业有限公司 2022-09-13 CN claimed
CN-113214339-A Panaxadiol derivatives, preparation method and medical application thereof 延边大学 2021-08-06 CN claimed
CN-110940740-A Detection method of L- α -glycerophosphorylcholine isomer 上海现代制药海门有限公司 2020-03-31 CN claimed
CN-110128301-A A kind of blue-green alge remover and its environment-friendly preparation method thereof 上海裕兰生物科技有限公司 2019-08-16 CN claimed
EP-3256508-A1 PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS WITH HIGH STABILITY Covestro Deutschland AG (DE) 2017-12-20 EP claimed
CN-106046100-A 17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl derivatives, methods for the production thereof and the use thereof for treating diseases 拜耳知识产权有限责任公司 2016-10-26 CN claimed
WO-2016128380-A1 PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS WITH HIGH STABILITY COVESTRO DEUTSCHLAND AG (DE) 2016-08-18 WO claimed
CN-102105149-A Substituted carbamate derivatives as modulators of corticotropin-releasing factor receptor activity BRISTOL MYERS SQUIBB CO 2011-06-22 CN claimed
CN-101166733-A Pyrazole derivatives as phosphodiesterase 4 inhibitors MEMORY PHARM CORP (US) 2008-04-23 CN claimed
CN-1890216-A Carboxylic acid amine derivatives MERCK PATENTE GES MIT BESCHRON (DE) 2007-01-03 CN claimed
US-6946557-B2 Process for producing optically active ethyl (3R, 5S, 6E)-7-[2-cycloproply-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxy-6-heptenoate DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2005-09-20 US claimed
CN-1204122-C Process for the isolation of optically active ethyl (3R,5S,6E) -7- [ 2-cyclopropyl-4- (4-fluorophenyl) quinolin-3-yl ] -3, 5-dihydroxy-6-heptenoate NISSAN CHEMICAL IND LTD (JP) 2005-06-01 CN claimed
US-20050075502-A1 Process for producing optically active ethly (3r, 5s, 6e)-7- [2-cycloproply-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxy-6-heptenoate NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-04-07 US claimed
CN-1468223-A Process for producign optically active ethyl (3r,5s,6e)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxy-6-heptenoate 大赛璐化学工业株式会社 2004-01-14 CN claimed
EP-1334967-A1 PROCESS FOR PRODUCIGN OPTICALLY ACTIVE ETHYL (3R,5S,6E)-7- 2-CYCLOPROPYL-4-(4-FLUOROPHENYL)QUINOLIN-3-YL]-3,5-DIHYDROXY-6-HEPTENOATE Daicel Chemical Industries, Ltd. (JP) 2003-08-13 EP claimed
EP-0161989-B1 COMPOSITIONS FOR THE TREATMENT OF FRUITS AND VEGETABLES BY THERMAL FOGGING AND TREATMENT PROCESS USING THESE COMPOSITIONS XEDA INTERNATIONAL (FR) 1988-08-10 EP claimed
CN-122031506-A Chiral control 波涛生命科学有限公司 2026-05-15 CN disclosed
CN-118922409-A Asymmetric piperazine-based cationic lipids 翻译生物公司 2024-11-08 CN disclosed
EP-0401817-A2 Reagents for rapid peptide synthesis RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1990-12-12 EP disclosed
US-3954967-A Method of producing microcolloidal aqueous emulsions of unsaturated organic insecticidal compounds VANGUARD CHEMICAL COMPANY, INC. (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050075502-A1 Process for producing optically active ethly (3r, 5s, 6e)-7- [2-cycloproply-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxy-6-heptenoate CNPY3, CYP8B1, HPD MEN1 4620/4885KMT2A 4367/4885KIF11 1572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.