Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 3/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | EPOR | P19235 | 2/20 | 0.33 |
| ▸ | NPY1R | P25929 | 2/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119581 | 0.91 | NPY1R (0.40) | EPORNPY1R | |
| SCHEMBL8120746 | 0.90 | TDP1 (0.34) | TDP1MEN1KMT2AEPORNPY1R | |
| SCHEMBL8114831 | 0.89 | EPOR (0.39) | TDP1KMT2AEPORNPSR1 | |
| SCHEMBL8526325 | 0.89 | MAPT (0.35) | TDP1MEN1KMT2AEPORNPY1R | |
| SCHEMBL8119418 | 0.88 | NPY1R (0.32) | TDP1EPORNPY1RMC4RMAPT | |
| SCHEMBL8122527 | 0.88 | NPY1R (0.38) | EPORNPY1R | |
| SCHEMBL8120388 | 0.88 | NR3C2 (0.34) | TDP1EPORNPY1R | |
| SCHEMBL8127365 | 0.86 | LMNA (0.41) | MEN1KMT2AMAPTHTTNPSR1 | |
| SCHEMBL8127523 | 0.86 | NPY1R (0.33) | MEN1KMT2AEPORNPY1RMAPT | |
| SCHEMBL8111322 | 0.86 | NPY1R (0.32) | MEN1KMT2ANPY1RMC4RMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |