Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 10/20 | 0.33 |
| ▸ | EPOR | P19235 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8111322 | 0.92 | NPY1R (0.32) | NPY1RMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8121415 | 0.90 | CTSD (0.36) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8119581 | 0.88 | NPY1R (0.40) | NPY1REPOR | |
| SCHEMBL8112912 | 0.88 | CTSD (0.36) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8120144 | 0.88 | EPOR (0.35) | NPY1REPORMEN1KMT2A | |
| SCHEMBL8127365 | 0.87 | LMNA (0.41) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8122527 | 0.86 | NPY1R (0.38) | NPY1REPOR | |
| SCHEMBL8126142 | 0.86 | TDP1 (0.35) | NPY1REPORMEN1KMT2AMAPT | |
| SCHEMBL8114831 | 0.85 | EPOR (0.39) | EPORKMT2AALDH1A1NPSR1 | |
| SCHEMBL8120799 | 0.85 | EPOR (0.42) | EPORMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |