Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8117900 | 1.00 | SIGMAR1 (0.69) | SIGMAR1L3MBTL1DRD3DRD2 | |
| SCHEMBL8118831 | 0.96 | SIGMAR1 (0.75) | SIGMAR1L3MBTL1DRD3DRD2 | |
| SCHEMBL8125746 | 0.90 | OPRK1 (0.62) | SIGMAR1L3MBTL1 | |
| SCHEMBL8126666 | 0.88 | SIGMAR1 (0.67) | SIGMAR1L3MBTL1DRD3DRD2 | |
| SCHEMBL8120009 | 0.86 | SIGMAR1 (0.75) | SIGMAR1L3MBTL1DRD3DRD2 | |
| SCHEMBL8126235 | 0.86 | SIGMAR1 (0.75) | SIGMAR1L3MBTL1DRD3DRD2 | |
| SCHEMBL8127075 | 0.86 | SIGMAR1 (0.75) | SIGMAR1L3MBTL1DRD3DRD2 | |
| SCHEMBL8124961 | 0.85 | SIGMAR1 (0.74) | SIGMAR1L3MBTL1DRD3DRD2 | |
| SCHEMBL8120171 | 0.85 | SIGMAR1 (0.93) | SIGMAR1L3MBTL1DRD3DRD2 | |
| SCHEMBL8120491 | 0.85 | SIGMAR1 (0.74) | SIGMAR1L3MBTL1DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861252-B1 | NAPHTHAMIDE DERIVATIVES OF 3 BETA-AMINO AZABICYCLO OCTANE OR NONANE AS NEUROLEPTIC AGENTS | PF MEDICAMENT (FR) | 2000-02-23 | — | — | EP | disclosed |