SCHEMBL812660

SCHEMBL812660

C=CCC(O)(CC=C)C(CO)(CO)C(O)(CC=C)CC=C

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL901347 0.80 TSHR (0.37) TSHR
SCHEMBL29249183 0.78 TSHR (0.38) TSHR
SCHEMBL28387645 0.78 TSHR (0.35) TSHR
SCHEMBL19148667 0.72 TSHR (0.30) TSHR
SCHEMBL1420315 0.71
SCHEMBL9238628 0.71 TSHR (0.39) TSHR
SCHEMBL31518968 0.70
SCHEMBL2426672 0.70
SCHEMBL4305849 0.69 ALDH1A1 (0.37) TSHR
SCHEMBL11507676 0.69 NR1H2 (0.31) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9084739-B2 Cross-linked copolymer containing phosphorylcholine monomer and cosmetic composition containing same KCI LIMITED (KR) 2015-07-21 US claimed
EP-2403884-B1 NON-HYDROCARBYL HYDROPHOBICALLY MODIFIED POLYCARBOXYLIC POLYMERS HERCULES INC (US) 2014-09-10 EP claimed
US-8623977-B2 Non-hydrocarbyl hydrophobically modified polycarboxylic polymers HERCULES INCORPORATED (US) 2014-01-07 US claimed
EP-2662070-A2 CROSS-LINKED COPOLYMER CONTAINING PHOSPHORYLCHOLINE MONOMER AND COSMETIC COMPOSITION CONTAINING SAME KCI Limited. (KR) 2013-11-13 EP claimed
US-20130295038-A1 Cross-Linked Copolymer Containing Phosphorylcholine Monomer and Cosmetic Composition Containing Same KCI LIMITED (KR) 2013-11-07 US claimed
US-20100130711-A1 NON-HYDROCARBYL HYDROPHOBICALLY MODIFIED POLYCARBOXYLIC POLYMERS HERCULES INCORPORATED (US) 2010-05-27 US claimed
US-9499505-B2 Process for the epoxidation of olefins CHANG CHUN PLASTICS CO., LTD. (TW) 2016-11-22 US disclosed
US-20160177023-A1 CONTINUOUS PROCESS OF OLEFINIC EPOXIDATION BY SUPPORTED HETEROPOLY ACID CHANG CHUN PLASTICS CO., LTD. (TW) 2016-06-23 US disclosed
EP-3019064-A1 TOILET SCRUBBER AND TOILET CLEANER 3M Innovative Properties Company (US) 2016-05-18 EP disclosed
US-20160106274-A1 TOILET SCRUBBER AND TOILET CLEANER 3M INNOVATIVE PROPERTIES COMPANY 2016-04-21 US disclosed
US-20160083360-A1 PROCESS FOR THE EPOXIDATION OF OLEFINS CHANG CHUN PLASTICS CO., LTD. (TW) 2016-03-24 US disclosed
US-9084739-B2 Cross-linked copolymer containing phosphorylcholine monomer and cosmetic composition containing same KCI LIMITED (KR) 2015-07-21 US disclosed
EP-2403884-B1 NON-HYDROCARBYL HYDROPHOBICALLY MODIFIED POLYCARBOXYLIC POLYMERS HERCULES INC (US) 2014-09-10 EP disclosed
US-8623977-B2 Non-hydrocarbyl hydrophobically modified polycarboxylic polymers HERCULES INCORPORATED (US) 2014-01-07 US disclosed
EP-2662070-A2 CROSS-LINKED COPOLYMER CONTAINING PHOSPHORYLCHOLINE MONOMER AND COSMETIC COMPOSITION CONTAINING SAME KCI Limited. (KR) 2013-11-13 EP disclosed
US-20130295038-A1 Cross-Linked Copolymer Containing Phosphorylcholine Monomer and Cosmetic Composition Containing Same KCI LIMITED (KR) 2013-11-07 US disclosed
EP-2403884-A1 NON-HYDROCARBYL HYDROPHOBICALLY MODIFIED POLYCARBOXYLIC POLYMERS Hercules Incorporated (US) 2012-01-11 EP disclosed
WO-2010059765-A1 NON-HYDROCARBYL HYDROPHOBICALLY MODIFIED POLYCARBOXYLIC POLYMERS HERCULES INCORPORATED (US) 2010-05-27 WO disclosed
US-20100130711-A1 NON-HYDROCARBYL HYDROPHOBICALLY MODIFIED POLYCARBOXYLIC POLYMERS HERCULES INCORPORATED (US) 2010-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160083360-A1 PROCESS FOR THE EPOXIDATION OF OLEFINS HSF1, HMOX1, HSPH1 TSHR 3568/4885
US-20130295038-A1 Cross-Linked Copolymer Containing Phosphorylcholine Monomer and Cosmetic Composition Containing Same PHOSPHO1, SGMS1, SGMS2 TSHR 4578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.