Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI6 | Q6TGC4 | 2/20 | 0.48 |
| ▸ | PADI4 | Q9UM07 | 8/20 | 0.46 |
| ▸ | PADI2 | Q9Y2J8 | 5/20 | 0.43 |
| ▸ | KDM1A | O60341 | 6/20 | 0.42 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9286645 | 0.91 | MCHR1 (0.50) | PADI6PADI4PADI2KDM1APDE4A | |
| SCHEMBL8114285 | 0.91 | MCHR1 (0.50) | PADI6PADI4PADI2KDM1APDE4A | |
| SCHEMBL8122653 | 0.91 | PADI6 (0.42) | PADI6PADI4PADI2KDM1APDE4A | |
| SCHEMBL9284142 | 0.91 | PADI6 (0.42) | PADI6PADI4PADI2KDM1APDE4A | |
| SCHEMBL8112793 | 0.89 | NPY1R (0.54) | NPY1RMCHR1 | |
| SCHEMBL9285714 | 0.89 | NPY1R (0.54) | NPY1RMCHR1 | |
| SCHEMBL8126577 | 0.88 | NPY1R (0.44) | PADI6NPY1R | |
| SCHEMBL9280771 | 0.88 | NPY1R (0.44) | PADI6NPY1R | |
| SCHEMBL8121138 | 0.87 | NPY1R (0.41) | PADI6PADI4PADI2PDE4APDE4B | |
| SCHEMBL9289679 | 0.87 | NPY1R (0.41) | PADI6PADI4PADI2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |