Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 7/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PADI6 | Q6TGC4 | 2/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | PADI4 | Q9UM07 | 8/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | PADI2 | Q9Y2J8 | 4/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9289679 | 1.00 | NPY1R (0.41) | NPY1RF2PADI6NPY2RNPY5R | |
| SCHEMBL8126777 | 0.87 | PADI6 (0.48) | NPY1RPADI6PADI4MCHR1PADI2 | |
| SCHEMBL9285714 | 0.86 | NPY1R (0.54) | NPY1RNPY2RNPY5RMCHR1 | |
| SCHEMBL8112793 | 0.86 | NPY1R (0.54) | NPY1RNPY2RNPY5RMCHR1 | |
| SCHEMBL8126577 | 0.85 | NPY1R (0.44) | NPY1RPADI6NPY2RNPY5R | |
| SCHEMBL9280771 | 0.85 | NPY1R (0.44) | NPY1RPADI6NPY2RNPY5R | |
| SCHEMBL8115106 | 0.84 | CA2 (0.44) | NPY1RF2 | |
| SCHEMBL8114285 | 0.82 | MCHR1 (0.50) | PADI6PADI4MCHR1PADI2PDE4A | |
| SCHEMBL9286645 | 0.82 | MCHR1 (0.50) | PADI6PADI4MCHR1PADI2PDE4A | |
| SCHEMBL9284142 | 0.81 | PADI6 (0.42) | PADI6PADI4MCHR1PADI2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |