Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI6 | Q6TGC4 | 2/20 | 0.42 |
| ▸ | PADI4 | Q9UM07 | 10/20 | 0.41 |
| ▸ | PADI2 | Q9Y2J8 | 5/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122653 | 1.00 | PADI6 (0.42) | PADI6PADI4PADI2PDE4APDE4B | |
| SCHEMBL8126777 | 0.91 | PADI6 (0.48) | PADI6PADI4PADI2PDE4APDE4B | |
| SCHEMBL9286645 | 0.90 | MCHR1 (0.50) | PADI6PADI4PADI2PDE4APDE4B | |
| SCHEMBL8114285 | 0.90 | MCHR1 (0.50) | PADI6PADI4PADI2PDE4APDE4B | |
| SCHEMBL1388417 | 0.85 | PADI6 (0.44) | PADI6PADI4PADI2PDE4APDE4B | |
| SCHEMBL9285714 | 0.83 | NPY1R (0.54) | MCHR1 | |
| SCHEMBL8112793 | 0.83 | NPY1R (0.54) | MCHR1 | |
| SCHEMBL8126577 | 0.82 | NPY1R (0.44) | PADI6 | |
| SCHEMBL9280771 | 0.82 | NPY1R (0.44) | PADI6 | |
| SCHEMBL8115106 | 0.81 | CA2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |