Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121310 | 0.85 | NPY1R (0.50) | POLBNPY1R | |
| SCHEMBL1388313 | 0.83 | NPY1R (0.44) | NPY1RCNR1 | |
| SCHEMBL8119401 | 0.82 | CNR1 (0.48) | NPY1RCNR1CNR2C3AR1 | |
| SCHEMBL8120358 | 0.82 | CNR1 (0.51) | CNR1CNR2C3AR1 | |
| SCHEMBL5057899 | 0.82 | NPY1R (0.53) | NPY1R | |
| SCHEMBL8612664 | 0.80 | CNR1 (0.44) | NPY1RCNR1CNR2C3AR1 | |
| SCHEMBL4650707 | 0.80 | NPY1R (0.43) | NPY1RCNR1 | |
| SCHEMBL1388761 | 0.80 | NPY1R (0.51) | NPY1R | |
| SCHEMBL4651777 | 0.79 | CNR1 (0.48) | NPY1RCNR1ALDH1A1CNR2 | |
| SCHEMBL4651114 | 0.77 | NPY1R (0.45) | NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |