Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 17/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.49 |
| ▸ | NPY4R | P50391 | 2/20 | 0.49 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.48 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751683 | 0.85 | NPY1R (0.62) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8126877 | 0.85 | POLB (0.40) | NPY1RPOLB | |
| SCHEMBL8121634 | 0.84 | NPY1R (0.51) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8112679 | 0.83 | NPY1R (0.58) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL6899864 | 0.82 | NPY1R (0.71) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL7059807 | 0.82 | NPY1R (0.71) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8529342 | 0.82 | NPY1R (0.51) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL7746012 | 0.82 | NPY1R (0.61) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL650331 | 0.82 | NPY1R (0.72) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL4651828 | 0.82 | NPY1R (0.61) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | claimed |