SCHEMBL812696

SCHEMBL812696

CCC(C)S(=O)(=O)NCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.55
CA12 O43570 3/20 0.55
CA7 P43166 2/20 0.55
CA14 Q9ULX7 2/20 0.55
CA1 P00915 2/20 0.52
KEAP1 Q14145 1/20 0.50
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
ATM Q13315 1/20 0.47
CA9 Q16790 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
HTT P42858 1/20 0.46
ALDH1A1 P00352 3/20 0.44
LMNA P02545 2/20 0.42
KMT2A Q03164 1/20 0.42
KDM4E B2RXH2 1/20 0.42
POLB P06746 1/20 0.42
TSHR P16473 1/20 0.42
RECQL P46063 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL171653 0.83 CA2 (0.61) CA2CA12CA7CA14CA1
SCHEMBL19592287 0.81 L3MBTL1 (0.50) CA2CA12CA7CA14CA1
SCHEMBL22230834 0.80 HTT (0.56) CA2CA12CA14CA1CA9
SCHEMBL24767434 0.80 CA2 (0.57) CA2CA12CA7CA14CA1
SCHEMBL18594476 0.77 CA12 (0.53) CA2CA12CA7CA14CA1
SCHEMBL12256317 0.76 CA12 (0.61) CA2CA12CA7CA14CA1
SCHEMBL2112943 0.75 CA2 (0.65) CA2CA12CA7CA14CA1
SCHEMBL14191076 0.74 KEAP1 (0.50) CA2CA12CA1KEAP1CA9
SCHEMBL21536760 0.74 CA2 (0.53) CA2CA12CA7CA14CA1
SCHEMBL6660379 0.73 MAPT (0.56) CA2CA12CA7CA14CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9563075-B2 Method for manufacturing liquid crystal display device provided with front plate, and liquid crystal display device provided with front plate Konica Minolta, Inc. (JP) 2017-02-07 US disclosed
US-20130222720-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE PROVIDED WITH FRONT PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE PROVIDED WITH FRONT PLATE KONICA MINOLTA , INC. (JP) 2013-08-29 US disclosed
US-8445081-B2 Polarizing plate protective film, polarizing plate and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2013-05-21 US disclosed
US-8062562-B2 Method of producing a cellulose ester film KONICA MINOLTA OPTO, INC. (JP) 2011-11-22 US disclosed
US-7854864-B2 Method for manufacturing an optical film having a convexoconcave structure KONICA MINOLTA OPTO, INC. (JP) 2010-12-21 US disclosed
US-7751005-B2 Liquid crystal display apparatus KONICA MINOLTA OPTO, INC. (JP) 2010-07-06 US disclosed
US-7598257-B2 Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors INCYTE CORPORATION (US) 2009-10-06 US disclosed
US-20090202823-A1 Cellulose Ester Film, Polarizing Plate and Display MURAKAMI TAKASHI 2009-08-13 US disclosed
US-20080084523-A1 LIQUID CRYSTAL DISPLAY APPARATUS KONICA MINOLTA OPTO, INC. (JP) 2008-04-10 US disclosed
US-20080049324-A1 Polarizing plate protective film, polarizing plate and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2008-02-28 US disclosed
US-20070252293-A1 METHOD FOR MANUFACTURING AN OPTICAL FILM HAVING A CONVEXOCONCAVE STRUCTURE, OPTICAL FILM, WIRE GRID POLARIZER AND RETARDATION FILM KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070135461-A1 3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile; immune-related diseases, skin disorders, myeloid proliferative disorders, cancer INCYTE CORPORATION 2007-06-14 US disclosed
US-20070092663-A1 Cellulose ester film, polarizing plate and display KONICA MINOLTA OPTO, INC. 2007-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135461-A1 3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile; immune-related diseases, skin disorders, myeloid proliferative disorders, cancer JAK1, JAK3, MAP3K4 CA2 4789/4885CA12 4874/4885CA7 4518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.