Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | HTR2B | P41595 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 8/20 | 0.47 |
| ▸ | ACHE | P22303 | 8/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8133156 | 1.00 | HTR2A (0.48) | HTR2AHTR2CHTR2BSIGMAR1DRD2 | |
| SCHEMBL8132940 | 0.90 | BCHE (0.49) | BCHEACHEMAOAMAOBHDAC3 | |
| SCHEMBL8132943 | 0.90 | BCHE (0.49) | BCHEACHEMAOAMAOBHDAC3 | |
| SCHEMBL8129042 | 0.82 | BCHE (0.45) | DRD2BCHEACHEMAOAMAOB | |
| SCHEMBL8129045 | 0.82 | BCHE (0.45) | DRD2BCHEACHEMAOAMAOB | |
| SCHEMBL8131620 | 0.77 | ACHE (0.49) | HTR2ASIGMAR1DRD2BCHEACHE | |
| SCHEMBL8130052 | 0.77 | ACHE (0.50) | DRD2BCHEACHEMAOAMAOB | |
| SCHEMBL8119111 | 0.77 | BCHE (0.48) | BCHEACHE | |
| SCHEMBL8124394 | 0.74 | BCHE (0.51) | HTR2ABCHEACHE | |
| SCHEMBL8119499 | 0.73 | BCHE (0.46) | HTR2ASIGMAR1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610134-B1 | Indole derivatives as 5-HT1-like agonists | ADIR (FR) | 2000-04-05 | — | — | EP | disclosed |
| US-5348968-A | Migraines | ADIR ET COMPAGNIE (FR) | 1994-09-20 | — | — | US | disclosed |