Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 4/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 3/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8129143 | 1.00 | P2RX1 (0.39) | P2RX1TMPRSS4LMNAMAPTACP1 | |
| SCHEMBL8127022 | 0.89 | QPCTL (0.38) | P2RX1TMPRSS4LMNAMAPTQPCTL | |
| SCHEMBL8127023 | 0.89 | QPCTL (0.38) | P2RX1TMPRSS4LMNAMAPTQPCTL | |
| SCHEMBL8138723 | 0.83 | MEN1 (0.43) | LMNAMAPTQPCTLMEN1KMT2A | |
| SCHEMBL8138760 | 0.81 | ALDH1A1 (0.41) | P2RX1TMPRSS4LMNAMAPTACP1 | |
| SCHEMBL8138758 | 0.81 | ALDH1A1 (0.41) | P2RX1TMPRSS4LMNAMAPTACP1 | |
| SCHEMBL8135673 | 0.78 | EPHX2 (0.45) | P2RX1TMPRSS4LMNAMAPTQPCTL | |
| SCHEMBL8135675 | 0.78 | EPHX2 (0.45) | P2RX1TMPRSS4LMNAMAPTQPCTL | |
| SCHEMBL8134160 | 0.73 | TP53 (0.47) | P2RX1TMPRSS4LMNAMAPTMEN1 | |
| SCHEMBL8134161 | 0.73 | TP53 (0.47) | P2RX1TMPRSS4LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147098-A | USEFUL IN THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM, CARDIOVASCULAR SYSTEM, PULMONARY SYSTEM, GASTROINTESTINAL SYSTEM AND ENDOCRINOLOGIC SYSTEM | NOVO NORDISK A/S (DK) | 2000-11-14 | — | — | US | disclosed |