Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120234 | 0.91 | MEN1 (0.36) | STAT3MEN1KMT2A | |
| SCHEMBL143726 | 0.78 | TOP2A (0.39) | — | |
| SCHEMBL141817 | 0.76 | TOP2A (0.33) | MEN1KMT2A | |
| SCHEMBL143606 | 0.73 | KCNH2 (0.40) | — | |
| SCHEMBL142409 | 0.71 | GSK3B (0.37) | — | |
| SCHEMBL4466379 | 0.71 | P2RX7 (0.34) | — | |
| SCHEMBL3134076 | 0.71 | KCNH2 (0.38) | — | |
| SCHEMBL7489369 | 0.71 | STAT3 (0.40) | STAT3 | |
| SCHEMBL143976 | 0.71 | GSK3B (0.36) | — | |
| SCHEMBL3337171 | 0.71 | KCNH2 (0.41) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561850-B1 | 7-SUBSTITUTED-6-FLUORO-1,4-DIHYDRO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | NAEJA PHARMACEUTICAL INC (CA) | 2000-07-12 | — | — | EP | disclosed |