SCHEMBL22124696

SCHEMBL22124696

Cc1cc(C)c(S(=O)(=O)Nc2ccc(S(=O)(=O)c3ccc(NC(=O)Nc4ccccc4)cc3)cc2)c(C)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 4/20 0.58
GPR27 Q9NS67 2/20 0.57
AVPR2 P30518 1/20 0.57
POLB P06746 2/20 0.57
GAA P10253 2/20 0.57
TSHR P16473 1/20 0.57
GFER P55789 1/20 0.57
MAPT P10636 4/20 0.56
RAB9A P51151 1/20 0.56
LMNA P02545 5/20 0.54
ALDH1A1 P00352 2/20 0.51
ALOX12 P18054 3/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
TP53 P04637 1/20 0.51
XBP1 P17861 1/20 0.51
HTT P42858 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
GHSR Q92847 1/20 0.50
LIPG Q9Y5X9 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30657899 0.82 RAPGEF4 (0.64) MAPTRAB9ALMNAALDH1A1MEN1
SCHEMBL812919 0.82 TSHR (0.70) POLBGAATSHRGFERMAPT
SCHEMBL23412517 0.81 MEN1 (0.69) GAAGFERLMNAALDH1A1MEN1
SCHEMBL17102986 0.80 CA12 (0.76) GPR27AVPR2POLBGAAGFER
SCHEMBL9913185 0.79 CA12 (0.73) TSHRMAPTRAB9ALMNAALDH1A1
SCHEMBL28610480 0.79 GHSR (0.65) IDH1POLBGAAGFERMAPT
SCHEMBL12010876 0.78 MEN1 (0.72) GPR27GAAGFERLMNAALDH1A1
SCHEMBL12010905 0.78 CA12 (0.71) TSHRMAPTRAB9ALMNAALDH1A1
SCHEMBL29767881 0.78 UQCRB (0.64) POLBGAAGFERMAPTLMNA
SCHEMBL22125137 0.77 CA12 (0.76) GPR27GAAGFERMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113260517-B Thermosensitive recording material 奥古斯特科勒纸厂欧洲公司 2022-04-22 CN disclosed
EP-3898247-A1 HEAT-SENSITIVE RECORDING MATERIAL Papierfabrik August Koehler SE (DE) 2021-10-27 EP disclosed
CN-113260517-A Thermosensitive recording material 奥古斯特科勒纸厂欧洲公司 2021-08-13 CN disclosed
WO-2020127675-A1 HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2020-06-25 WO disclosed