Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126842 | 0.86 | DRD2 (0.48) | MEN1KMT2ANAMPTALDH1A1MAPT | |
| SCHEMBL4818137 | 0.78 | ALDH1A1 (0.70) | MEN1KMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL12574593 | 0.77 | ALDH1A1 (0.47) | KMT2ANAMPTALDH1A1POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4471670 | 0.77 | ALDH1A1 (0.68) | MEN1KMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL4772546 | 0.76 | NAMPT (0.49) | MEN1KMT2ANAMPTALDH1A1KDM4E | |
| SCHEMBL8135851 | 0.76 | PDE4B (0.42) | MEN1NAMPTALDH1A1KDM4EMAPT | |
| SCHEMBL8125595 | 0.74 | MEN1 (0.55) | MEN1KMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL8133405 | 0.74 | ACHE (0.58) | — | |
| SCHEMBL8132361 | 0.73 | MEN1 (0.55) | MEN1KMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL14544155 | 0.73 | NAMPT (0.53) | MEN1KMT2ANAMPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664291-B1 | PYRIMIDINE COMPOUND | UBE INDUSTRIES (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5610303-A | MONOAMIDE OXIDASE INHIBITORS | UBE INDUSTRIES, LTD. (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0664291-A1 | PYRIMIDINE COMPOUND | UBE INDUSTRIES, LTD. (JP) | 1995-07-26 | — | — | EP | disclosed |