SCHEMBL8129459

SCHEMBL8129459

COc1ccccc1N(C)CC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.50
POLB P06746 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
LMNA P02545 1/20 0.47
SLC6A9 P48067 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
ESR1 P03372 1/20 0.42
MEN1 O00255 1/20 0.42
CRHBP P24387 1/20 0.42
KMT2A Q03164 1/20 0.42
CRHR2 Q13324 1/20 0.42
ALDH1A1 P00352 2/20 0.42
PTGIR P43119 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3651761 0.84 TDP1 (0.70) TDP1POLBSMN1; SMN2LMNACA12
SCHEMBL12722766 0.83 TSPO (0.62) TDP1SMN1; SMN2LMNASLC6A2SLC6A4
SCHEMBL28005868 0.81 MAPT (0.44) TDP1POLBSMN1; SMN2LMNAESR1
SCHEMBL12956486 0.80 HSD17B10 (0.46) POLBSMN1; SMN2LMNAMEN1KMT2A
SCHEMBL12956478 0.79 ALDH1A1 (0.56) SMN1; SMN2MEN1KMT2AALDH1A1NPC1
SCHEMBL4607462 0.79 ALDH1A1 (0.46) TDP1POLBSMN1; SMN2LMNACA12
SCHEMBL3948272 0.78 NOTUM (0.50) TDP1LMNAMEN1KMT2AALDH1A1
SCHEMBL6315253 0.78 ALDH1A1 (0.37) TDP1POLBSMN1; SMN2LMNASLC6A9
SCHEMBL27713586 0.78 ESR1 (0.51) TDP1POLBSMN1; SMN2ESR1MEN1
SCHEMBL8779753 0.77 TSPO (0.53) POLBSMN1; SMN2LMNACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4946761-A POLYMER CONTAINING CARBOXYL END GROUPS FUJI PHOTO FILM CO., LTD. (JP) 1990-08-07 US claimed
EP-0738269-B1 PIPERIDINE DERIVATIVES WITH PAF ANTAGONIST ACTIVITY URIACH & CIA SA J (ES) 2000-04-26 EP disclosed
EP-0458485-B1 Image forming layer FUJI PHOTO FILM CO LTD (JP) 1998-07-29 EP disclosed
US-5705504-A PLATELET ACTIVATING FACTOR J. URIACH & CIA, S.A. (ES) 1998-01-06 US disclosed
EP-0738269-A1 NOVEL PIPERIDINE DERIVATIVES WITH PAF ANTAGONIST ACTIVITY J. URIACH & CIA. S.A. (ES) 1996-10-23 EP disclosed
WO-1996014317-A1 NOVEL PIPERIDINE DERIVATIVES WITH PAF ANTAGONIST ACTIVITY J. URIACH & CIA. S.A. (ES) 1996-05-17 WO disclosed
US-5395733-A Unsaturated polymer layer that can be decarboxylated on exposure to light and sensitizers FUJI PHOTO FILM CO., LTD. (JP) 1995-03-07 US disclosed
EP-0458485-A2 Image forming layer Fuji Photo Film Co., Ltd. (JP) 1991-11-27 EP disclosed
US-4946761-A POLYMER CONTAINING CARBOXYL END GROUPS FUJI PHOTO FILM CO., LTD. (JP) 1990-08-07 US disclosed
US-4405705-A HYDROPHILIC TOYO BOSEKI KABUSHIKI KAISHA T/A TOYOBA CO., LTD. (JP) 1983-09-20 US disclosed